First codon of a messenger RNA transcript translated by a ribosome.
1
All the protein-coding genes begin with an ATG initiation codon except for COXI with GTG.
2
Their parents and healthy sister are heterozygous for the same variant that abolishes the translation initiation codon of GHR.
3
In vitro transcription and translation of short cDNA demonstrated that the AUG encoding Met27 is indeed a functional initiation codon.
4
This region contains the initiation codon for protein synthesis and coding information for 10 amino acids common to the two proteins.
5
Rare AGA or AGG codons close to the initiation codon inhibit protein synthesis by a tRNA-sequestering mechanism as toxic minigenes do.
1
The alternative in-frame start codon is not present around a mutation.
2
The CD21 promoter region contains a CpG island adjacent to the ATG start codon.
3
IRES A is located within the 300 nucleotides upstream from the AUG start codon.
4
The expression level and start codon correction were crucial for functional characterization of HU in Deinococcus.
5
The first mutation disrupted the start codon and the second mutation resulted in an amino acid substitution.
6
Mutations were made such that the DNA sequence upstream of the ATG start codon was not changed.
7
DNA sequence analysis revealed a point mutation in the start codon of sigK in all low-producing BCG strains.
8
As a consequence, another start codon is predicted, resulting in a decrease in size of the signal peptide.
9
Six exons, 1a-1f, lie upstream of the translation start codon in exon 2.
10
The second alternatively spliced version harbors a completely shifted open reading frame with a potential new ATG start codon.
11
We hypothesize that long range tertiary interactions in the VEGF mRNA regulate IRES activity and thus control start codon selection.
12
We show that 240 bp upstream of the translation start codon are sufficient for the transcription of the lacZ gene.
13
The sequence of about 600 nucleotides upstream from the start codon of the protease gene was determined for both strains.
14
The DNA sequencing analysis revealed a major transcriptional start site at 72 base pairs in front of the ATG translational start codon.
15
In summary, we identified a novel start codon mutation within the FRMD7 gene of 2 Korean families.
16
This mutation leads to the loss of the primary start codon ATG for methionine, which is replaced by a triplet GTG for valine.